Red Yeast Rice Extract Zowonjezera: Zopindulitsa, Mlingo, ndi Zotsatira Zotsatira

Kodi Red yisiti Mpunga Tingafinye

Red yisiti mpunga Tingafinye (RYRE) limapangidwa pamene mtundu wina wa nkhungu wotchedwa Monascus purpureus upaka mpunga. Mpunga umasanduka wakuda ndipo umapanga mankhwala omwe amadziwika kuti monacolin K omwe ali ndi phindu lamankhwala. RYRE wakhala gawo la TCM (mankhwala achikhalidwe achi China) kwazaka zoposa 10. Pakadali pano, imagulitsidwa ngati chowonjezera komanso monga chakudya chopatsa thanzi padziko lonse lapansi.

 

Kodi Red Yeast Rice Extract Zimagwira Bwanji Ntchito

HMG-CoA reductase enzyme ndi enzyme yomwe imatembenuza molekyulu yotchedwa HMG-CoA kukhala mevalonate. Mevalonate phula ndi nyumba yofunika kwambiri ya ma 1000 mamolekyulu ena, monga cholesterol. Monacolin K amagwiranso ntchito chimodzimodzi ndi lovastatin chifukwa amamangiriza HMG-CoA reductase yoletsa kupanga cholesterol.

Mevalonate amathanso kusinthidwa kukhala mamolekyu ofunikira monga coenzyme Q10 omwe amagwira ntchito ngati antioxidant.

RYRE ili ndi mankhwala ena kuphatikiza monacolin K. Imakhalanso ndi makina athunthu ovuta kuyerekeza ndi lovastatin. Malinga ndi asayansi, magawo ena a yisiti wofiira mpunga amatha kuchepetsa mavuto omwe amabwera chifukwa cha monacolin K. monga kufooka kwa minofu.

Kodi Risi Yotupitsa Imapikisanso Mankhwala Kapena Chowonjezera?

Red yisiti mpunga Tingafotokozere onse mankhwala ndi zowonjezera. Izi ndichifukwa choti chimodzi mwazofunikira kwambiri mu yisiti yofiira ya yisiti ndi monacolin K. Amatchulidwanso kuti lovastatin yomwe ndi gawo logwirika mu mankhwala omwe amatchedwa Mevacor. Chifukwa chake, RYRE kumbali imodzi ndi zowonjezera zomwe zimathandizira kutsika mafuta pomwe, Mevacor wopanga mankhwala akunena kuti ali ndi ufulu wokhala ndi chotengera cha lovastatin.

Chosakaniza cha lovastatin mu yisiti wampunga wofiira chimatchulidwanso monga mankhwala omwe FDA imapereka. Ichi ndichifukwa chake RYRE amagawidwa mosokoneza monga mankhwala ndiwowonjezera.

 

Ubwino Wopatsa Muyezo wa Yisiti

Zomwe takambirana pansipa ndi zina za yisiti yampira yofiyira phindu:

 

Mpunga wofiyira wofiyira amachepetsa ma Cholesterol

Kuchuluka kwa cholesterol choipa ndimavuto azaumoyo okhudzana ndi kunenepa kwambiri, matenda a shuga insulin kukana, sitiroko, kuthamanga kwa magazi, komanso matenda amtima. Njira imodzi yothandiza kwambiri kuchepetsa kuchuluka kwa mafuta m'thupi komanso kuteteza thupi lanu kumatendawa ndikudya chakudya chopatsa thanzi komanso kukhala ndi moyo wathanzi. Komabe, anthu ochepa amatha kukhala ndi cholesterol yoyipa mosasamala kanthu za izi.

Mpunga wofiyira wa yisiti kumayambitsa cholesterol yowongolera kumachitika chifukwa chakukula kwake kwa HDL (cholesterol yabwino) m'magazi ndikuchepetsa triglycerides ndi LDL (cholesterol yoyipa). Red yisiti mpunga zowonjezera zimalepheretsanso kulemera ndikuwonetsetsa kuchuluka kwa leptin ndi michere ya chiwindi.

Kafukufuku zingapo zomwe zimakhudza anthu pafupifupi 8,000 omwe adatenga nawo mbali, anthu omwe amatenga zofufumitsa za Red yisiti anali atatsitsa LDL (cholesterol yoyipa) ndi cholesterol yonse. Sanawonongekonso impso kapena chiwindi.

 

Red Yisiti Mpunga Imatsitsa Kutsitsa

Kutupa ndi yofala yofotokozedwa ndi chitetezo chathu cha mthupi chomwe chimapangidwa kuti titeteze matupi athu ku zinthu zakunja ndi matenda owopsa.

Kutupa kwanthawi yayitali komabe kumachitika kuti kumayambitsa matenda monga mtima, shuga, komanso khansa. Kafukufuku akuwonetsa kuti kutenga zofunikira za yisiti zampunga (RYRE) ingakuthandizireni kuchepa kwa kutupa ndikuthandizira thanzi lalitali.

Mwachitsanzo, kafukufuku wokhudzana ndi anthu 50 omwe ali ndi metabolic syndrome adatsimikiza kuti kutenga yisiti yofiira ya mpunga ndi kutsitsa maolivi kumachepetsa nkhawa za oxidative zomwe zimayambitsa matenda mpaka 20 peresenti.

Mofananamo, kafukufuku wina wa nyama adazindikira kuti makoswe okhala ndi kuwonongeka kwa impso komwe adadyetsa yisiti yofiira imayamwa ufa kutsitsa milingo yamapuloteni ena ake omwe amayenderana ndi kutupa.

 

Red Yeast Rice Extract Ili ndi Zida za Anticancer

Umboni wina wochokera ku kafukufuku wazinyama ndi ma cell umatsimikizira kuti yisiti yofiira ya yisiti imatha kuthandizira kuchepetsa kufalikira ndi kukula kwa maselo a khansa. Kafukufuku wina ananena kuti kupereka makoswe ndi khansa yachiwiri ya prostate kumayambitsa ufa wocheperako kumachepetsa zotupa poyerekeza ndi gulu lolamulira. …

Kafukufuku woyeserera adatsimikiziranso kuti kugwiritsa ntchito ufa wampira wofiyira wofufumitsa m'maselo a khansa ya prostate kumachepetsa kukula kwa maselo a khansa kwambiri kuposa lovastatin.

Mpunga wofiyira ofiira Umasintha Moyo Wathanzi

Kafukufuku wina wokhudza mbewa, mpunga wofiyira ofiira amachepetsa kuchepa kwa mafupa ndi mbewa. Mpunga wopangidwa ndi yisiti wofiyira anali ndi maselo abwinobwino am'mafupa komanso owonda kwambiri kuposa mafupa a placebo.

Kutulutsa mpunga wofiyira kumawonjezera mtundu wa BMP2, womwe ndi wofunikira kwambiri pakuchiritsa mafupa.

 

Mlingo wa Red yisiti Ratch

Kumbukirani kuti kuchuluka kwazofunikira kwambiri zomwe zimadziwika kuti monacolin zimatha kusiyanasiyana muzowonjezera za mpunga wofiira. Ichi ndichifukwa pali mitundu yambiri ya yisiti ndipo mitundu yosiyanasiyana ya nayonso mphamvu imagwiritsidwa ntchito. Kafukufuku wazopeza zofunikira za mpunga wofiira wosiyanasiyana adawonetsa kuti zomwe zili mu monacolin zimachokera ku zero mpaka 0.58 peresenti.

Ngakhale kafukufuku wosiyanasiyana adanenapo za yisiti yofiira ya mpunga yotulutsa mlingo, simungadziwe ngati mtundu womwe mukugwiritsa ntchito ukakhala ndi monacolin wokwanira. Ndikofunikira kuti nthawi zonse muziyang'ana monacolin zomwe zili muzowonjezera musanasankhe kuti ndi chiyani Mlingo wampira wofiyira kugwiritsa ntchito.

Ku TCM (Traditional Chinese Medicine), mulingo wampira wofiyira wovomerezeka ukhoza kukhala wapamwamba. Komabe, maphunziro ena agwiritsa ntchito mpunga wofiyira wofiyira amachotsa mlingo wa 600 mg kanayi patsiku. Maphunziro ena amalimbikitsanso kutenga yisiti yofiira ya yisiti kuchotsa 1200 mg kawiri patsiku.

 

Red Yeast Rice Extract Mbali Zotsatira

Zomwe tafotokozazi pansipa ndi zina mwazotsatira zofunikira za mpunga;

Mwa anthu ambiri, mpunga wa Red yisiti umakhala wotetezeka mukamamwa pakadutsa zaka zinayi ndi miyezi isanu ndi umodzi. Izi zikugwirizana ndi National Institutes of Health (NIH).

Lovastatin imapezeka muzinthu zosiyanasiyana za yisiti yofiira. Kuchuluka kwambiri kwa Tingafinye kumapangitsa kuti pakhale mavuto osiyanasiyana monga yisiti yofiira ya mpunga monga kuwonongeka kwambiri kwa minofu ndikuwonongeka kwa chiwindi ndi impso. Lovastatin yomwe imakhala yopanda yisiti yofiira imatha kuwonetsa zovuta zina.

Citrinin ikhozanso kupezeka ndi yisiti wofiira mpunga ikafufumitsidwa molakwika. Citrinin ndichinthu choopsa ndipo chitha kuwononga impso. Matenda ena a yisiti wofiira atha kuphatikizira kutentha pa chifuwa, kupweteka kwa mutu komanso kukhumudwa m'mimba.

 

Red Yeast Rice Extract Drug Interaction

 

Mankhwala omwe amachepetsa cholesterol

Pokhapokha mutapatsidwa mankhwala ndi dokotala, simuyenera kudya mpunga wofiyira limodzi ndi mankhwala omwe amachepetsa cholesterol. Mpunga ofiira ungalimbitse mphamvu ya mankhwalawa. Izi zimapangitsa kuti chiwopsezo chowononga chiwindi chikhale chokulirapo. Ngati muli pansi pa statin kapena mankhwala ena aliwonse otsitsa mafuta a cholesterol, funsani dokotala musanatenge mpunga wofiira.

 

Gawo la Coenzyme Q10 (CoQ10)

Mipata ya CoQ10 ikhoza kutsitsidwa ndi ma statins. CoQ10 ndikofunikira kwambiri pa thanzi la minofu ndi mtima. Zimathandizanso pakupanga mphamvu. Kuperewera kwa CoQ10 kokwanira kumatha kubweretsa kutopa, kupweteka kwa minofu, kuwonongeka ndi zopweteka. Kuphatikiza apo, yisiti wofiira mpunga amachepetsa ndalama za CoQ10 mthupi. Ngati mungafune kutenga CoQ10 ndipo mukugwiritsabe ntchito yisiti wofiira mpunga, funsani dokotala wanu.

Mpunga Wosakaniza Mpunga Wofiira

Zowonjezera zomwe zimakhala ndi mpunga wa yisiti wofiira zakhala zikugulitsidwa ku US kwanthawi yayitali. Amachepetsa cholesterol ndi lipids zina m'mitsempha yamagazi amunthu. Zaka zaposachedwa pomwe zambiri zopezeka mu 2008 ndi 2009. Zakudya zowonjezera ya mpunga ofiira pafupifupi anagulitsidwa $ 20 miliyoni chaka chilichonse. Malinga ndi National Health Mafunso Kafukufuku amene adachitika mchaka cha 2007, anthu 1.8 miliyoni omwe anali aku America adagwiritsa ntchito cholesterol yotsitsa mafuta.

Muyenera kusamala pogula zowonjezera izi chifukwa zinthu zina makamaka kuchokera kwa ogulitsa osavomerezeka sizotetezeka. Zina mwazowonjezera izi zimakhala ndi zodetsa zomwe zitha kukhala zovulaza.

 

Red yisiti mpunga Tingafinye kumene kugula

Ngati mukufuna kugula yofunikira kwambiri yisiti yampunga yowonjezera, chonde kulimbikira pa intaneti ndikuyang'ana kampani yomwe ili ndi zaka zambiri yopanga mankhwala azitsamba. Yang'anani a kampani yomwe yawononga kwambiri ndalama zogulira zida zamakono zopangira zinthu.

 

Zothandizira:

1. Zhao SP, Lu ZL, et al. Xuezhikang, wopeza cholestin, amachepetsa zochitika zamtima mu mtundu wa 2 odwala omwe ali ndi matenda a mtima: kupenda kwapafupipafupi kwa odwala omwe ali ndi matenda ashuga a 2 ochokera ku China coronary sekondale kupewa (CCSPS). J Cardiovasc Pharmacol. 2007 Feb; 49 (2): 81-84.
2. Peng D, Fong A, Pelt AV (2017). "Kafukufuku Wapachiyambi: Zotsatira Zowonjezera Mpunga Wosakaniza Mpunga Wofiyira Pamiyeso ya Cholesterol Kwa Akuluakulu" Ndine J Nurs. 117 (8): 46-54. .
3. Wang J, Lu Z, Chi J, Wang W, Su M, Kou W, et al. Multicenter matenda oyeserera a seramu lipid-kutsitsa zotsatira za Monascus aimureus (ofiira yisiti) mpunga pokonza mankhwala achi China. Curr Ther Res. 1997; 58 (12): 964-978.

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